Synapse BV is a working group within the Cardiovascular Research Institute Maastricht (CARIM) as well as a company within the Maastricht University Holding. It carries out developmental research in the field of the (patho-)physiology of haemostasis and thrombosis, operating in the niche between biochemistry and molecular biology on the one side and pharmaceutical- and clinical sciences on the other. It more specifically explores the overall function of the thrombin generating system in platelet poor- and platelet rich plasma and blood as a diagnostic tool and a pharmaceutical target. It cooperates with major pharmaceutical and diagnostic companies on such subjects as the mechanism of action of antiplatelet drugs and clotting factor inhibitors, the measurement of their effects in vitro and in vivo in animals and humans, as well as the development of diagnostic procedures based on the assessment of the overall function of the coagulation mechanism.
The synapse staff,
| Prof.
HC Hemker, MD, PhD Director |
Raed Al Dieri,
PhD Director Research, Pharmacist |
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| Prof. S. Béguin, PhD | R.
Wagenvoord, PhD Senior Scientist |

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Address Synapse BV University Maastricht P.O. Box 616 6200 MD, Maastricht The Netherlands |
Visiting/Delivery Address Synapse BV Oxfordlaan 70 6229 EV, Maastricht The Netherlands |
Phone:+31 (0)43 3885892 Fax: +31 (0)43 3884159 Email: info@thrombin.com |